It covers an area of approximately 2,850 square kilometers (1,100 square miles.) The landscape is composed of granitic ridges, river valley, and swamps. Vegetation is a mix of Acacia woodland, Combretum woodland, seasonally flooded grassland, and baobab trees.

Tarangire National Park lies 120 km south of Arusha, The most common animals found in the park include zebras, wildebeest, lions, leopards, waterbucks, giraffe, elephants, gazelles, impala, gerenuk, lesser kudu and the beautiful fringe-eared oryx. You may be lucky to spot the tree-climbing python, for which the park is famous, or the greater kudu and the roan antelope which are rare species in Northern Tanzania. Over 550 bird species have been recorded in the Park.